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Aim
This randomised, double blind, placebo controlled study examined the effects of Lab4 probiotics on general feelings of anxiety, mood and cognitive function in healthy individuals.
Method
- The study took place at the School of Psychology at Keele University.
- 50 healthy volunteers (19-38 years old, BMI<30) were divided into two groups.
- One group was supplemented with 50 billion Lab4 probiotics every day for six weeks.
- The second group took a placebo daily for 6 weeks.
- Volunteers completed mood and anxiety questionnaires (Bond Lader Mood Scales, Stait Trait Anxiety Inventory)
- Participants also completed a comprehensive computerised cognitive battery of tests (COMPASS)
The results
‘Trait’ Anxiety
(individual’s tendency to experience anxiety in response to the anticipation of a future threat, how individuals felt over the previous 6 weeks)
- Lab4 probiotics significantly decreased ‘trait’ anxiety levels compared to the placebo group, where the ‘trait’ anxiety levels increased over the course of the 6 weeks supplementation (P=0.042).
‘Continuity of attention’
(ability to focus and avoid distraction)
- ‘Continuity of attention’ significantly increased in response to the Lab4 supplementation and decreased in the placebo group (P=0.035).
Conclusion
The study showed the benefit of Lab4 probiotics for cognitive function in healthy individuals.
Reference
Owen L, et al 2014.
A double blind, placebo controlled, randomised pilot trial examining the effects of probiotic administration on mood and cognitive function.
Proceedings of the Nutrition Society 2014, 73 (OCE1): E29
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