Probiotic administration enhances expression of tight junction proteins
5 Lactobacillus and 5 Enterococcus strains isolated from infant gut microbiome were administered in this study to ageing mice. Bacterial genomic DNA was isolated from collected faeces and analysed alongside metabolites of gut bacteria. This study comprehensively demonstrates how a probiotic therapy modulates gut microbiota to enhance the abundance of beneficial metabolites like taurine, which reduces leaky gut and improves a healthy life span. This study concluded that a human origin probiotic therapy prevented metabolic dysfunctions — namely glucose intolerance, insulin resistance, hepatic steatosis, and fat tissue inflammation, in older mice. Further human studies may provide ground breaking treatment for thousands of people nationwide.
Shokouh Ahmadi et al. A human-origin probiotic cocktail ameliorates aging-related leaky gut and inflammation via modulating the microbiota/taurine/tight junction axis. JCI Insight 2020;5(9):e132055. https://doi.org/10.1172/jci.insight.132055.
Want to know more?
Pro-Ven Probiotics aim to provide the best support for both you and your health. If you wish to know more about gut health and staying healthy please do not hesitate to call us on 01639 825107 or alternatively, learn more via our blogs or in-depth proven research.
ProVen Probiotics, Unit 2 Christchurch Road, Baglan Industrial Park, Port Talbot, SA12 7DJ. Tel: 01639 825107