Gut bacteria can deactivate Cholera progression
This study identified one bacterium in the human microbiome, Blautia obeum, that can deactivate Cholera bacterium’s disease-causing mechanisms. Bile salt hydrolase, was seen to be degraded, reducing expression of virulence genes. A focus of future studies will be focused on how to increase its presence in the gut.
Salma Alavi, Jonathan D. Mitchell, Jennifer Y. Cho, Rui Liu, John C. Macbeth, Ansel Hsiao. Interpersonal Gut Microbiome Variation Drives Susceptibility and Resistance to Cholera Infection. Cell, 2020; 181 (7): 1533 DOI: 10.1016/j.cell.2020.05.036
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