Eubacterium Limosum linked to a reduction in clogged arteries and heart disease

This study found that Eubacterium limosum had the ability to reduce the toxicity of Trimethylamine (TMA) production in the gut (TMA contributes to clogged arteries and atherosclerosis). It did this specifically by the interaction of the enzyme Mtcb with L-Carnitine via demethylation. An exciting finding as this promises other future health benefits.

Krzycki et al. Mtcb a member of the MttB superfamily from the human gut acetogen Eubacterium limosum, is a cobalamin dependent carnitine demethylase. Journal of Biological Chemistry, 2020; doi: 10.1074/jbc.RA120.012934

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