GI and multisensory processing and adaptive functioning improved with bacterial complex

A 6-month double blind randomized, efficacy-controlled trial, supplementing with a (patented as DSF) 45o billion CFU of 8 probiotic strains.  63 children aged 18-72 months with ASD diagnosis were in involved in the trial, carried out in Tuscany, Italy. A significant decline in clinical observations of Autism Diagnostic Observation Schedule (ADOS) and Calibrated Severity Score (CSS) were found, along with improved GI symptoms.

Santocchi E, Guiducci L, Prosperi M, Calderoni S, Gaggini M, Apicella F, Tancredi R, Billeci L, Mastromarino P, Grossi E, Gastaldelli A, Morales MA and Muratori F (2020) Effects of Probiotic Supplementation on Gastrointestinal, Sensory and Core Symptoms in Autism Spectrum Disorders: A Randomized Controlled Trial. Front. Psychiatry 11:550593. doi: 10.3389/fpsyt.2020.550593

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