A recent meta-analysis of 38 randomised controlled clinical trials evaluated the effects of probiotics, prebiotics or synbiotics supplementation on metabolic outcomes in 2086 individuals with diabetes mellitus. Significant reductions in fasting blood glucose, total cholesterol, triacylglycerols and insulinaemia were observed. The supplementation with probiotics, prebiotics or synbiotics increased HDL-cholesterol levels.

Bock PM et al. The effect of probiotics, prebiotics or synbiotics on metabolic outcomes in individuals with diabetes: a systematic review and meta-analysis. Diabetologia 2020. https://doi.org/10.1007/s00125-020-05295-1

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