The gut microbiota in obesity

Meta-analysis of 25 clinical trials with 1931 obese subjects revealed that probiotic supplementation effectively reduced body weight. The study also demonstrated that a minimum of 8 weeks of multistrain probiotic intervention reduced body weight in obese subjects compared to single strain intervention. Overall, they concluded that probiotic supplementation improved intestinal permeability, increased O2 uptake by adipose cells and decreased endotoxin release and inflammation. Furthermore, thermogenesis and glucose and lipid metabolism were regulated.


Bhagavathi Sundaram Sivamaruthi, Periyanaina Kesika, Natarajan Suganthy, Chaiyavat Chaiyasut, “A Review on Role of Microbiome in Obesity and Antiobesity Properties of Probiotic Supplements”, BioMed Research International, vol. 2019, Article ID 3291367, 20 pages, 2019.

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