Metabolic disease indicated by gut microbes

This study was carried out in South Korea, with 747 overweight or obese adults who were split into 317 metabolically healthy – young with lower BMIs & bodyweight (MH) and 430 metabolically unhealthy – older with higher BMIs and bodyweight (MU). Their results showed that metabolic health was associated with gut microbiota composition and abundance in the obese/overweight population. Diversity of bacteria was lower in the MU group than the MH group. Gut microbiome diversity was negatively correlated with triglyceride (TG) level and positively correlated with high density lipoprotein cholesterol (HDL) level. Further research is required into the effects of the microbiome on metabolism in obese individuals, as these mechanisms likely play a key role in preventing metabolic disease.

Kim, MH., Yun, K.E., Kim, J. et al. Gut microbiota and metabolic health among overweight and obese individuals. Sci Rep 10, 19417 (2020).

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