Understanding the composition of a healthy gut microbiome.
In this study, 4347 publicly available, metagenomic data of gut microbiomes were taken from 34 published studies. 50 microbial species associated with human health were identified from stool samples. From this, the Gut Microbiome Health Index (GMHI) was formed, differentiating between a healthy gut microbiome and a diseased one. Results highlighted a correlation between a high GMHI and high HDL levels. There are some flaws to the methodology but this potentially a useful diagnostic tool for the future.
Gupta, V.K., Kim, M., Bakshi, U. et al. A predictive index for health status using species-level gut microbiome profiling. Nat Commun 11, 4635 (2020). https://doi.org/10.1038/s41467-020-18476-8
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