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20% Off Sale Women’s Probiotics

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The Ultra Marathon Study

Efficacy of Lab4 probiotics in the Marathon des Sables


This study aimed to assess the effect of a 12-week probiotic supplementation on race time and extracellular heat shock protein response to a multi-day ultra-endurance exercise event.


  • Thirty-two Marathon des Sables 2015 competitors (mean age 41 years) were divided into three groups.
  • The volunteers were supplemented for 12 weeks:
    Group 1 (n=11) maintained their regular diet
    Group 2 (n=11) took daily 1 capsule of 30 billion Lab4 probiotics
    Group 3 (n=10) took daily 5 g of powder comprised of 5 billion Lab4 probiotics, 5 billion Lactobacillus salivarius CUL61 and 0.9 g L-glutamine
  • After 12 weeks supplementation, the volunteers undertook the Marathon des Sables (294.4 km, 7-day ultra-marathon, across the Southern Moroccan portion of Sahara Desert, max temperature 39ยฐC).


Race times
  • The completion time in Group 2 (Lab4) was reduced by 5 h and 36 min compared to Group 1 (12% reduction; 2819 min in Group 1 vs. 2481 min in Group 2).
  • Fig 1: Time to completion (min)
  • The completion time with a lower dose of probiotics (Group 3) was reduced by 4 h and 9 min compared to Group 1 (9% reduction; 2819 min in Group 1 vs. 2570 min in Group 3, Figure 2).
  • Fig 2: Time to completion (min)
    Extracellular heat shock protein (eHsp72)
  • No differences in eHsp72 concentration were observed between groups during the study period.
  • Conclusion

    Lab4 probiotic supplementation improved the runnersโ€™ completion time during the ultra-marathon.


    Marshall H, Chrismas BC, Suckling CA, Roberts JD, Foster J, Taylor L. Chronic probiotic supplementation with or without glutamine does not influence the eHsp72 response to a multi-day ultra-endurance exercise event. Appl Physiol Nutr Metab 2017; 42(8): 876-883.

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